BDBM50293070 7-({[3-Hydroxy-2-(hydroxymethyl)propyl](methyl)amino}methyl)-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one::CHEMBL490282

SMILES CN(CC(CO)CO)Cc1c[nH]c2c1nc[nH]c2=O

InChI Key InChIKey=AOFDJZQAOKXDRB-UHFFFAOYSA-N

Data  1 KI  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293070   

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandPNGBDBM50293070(7-({[3-Hydroxy-2-(hydroxymethyl)propyl](methyl)ami...)
Affinity DataKd:  3.70nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
Go to US Patent

TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
Industrial Research

US Patent
LigandPNGBDBM50293070(7-({[3-Hydroxy-2-(hydroxymethyl)propyl](methyl)ami...)
Affinity DataKd:  2.00E+3nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
Go to US Patent

TargetPurine nucleoside phosphorylase(Human)
Industrial Research

US Patent
LigandPNGBDBM50293070(7-({[3-Hydroxy-2-(hydroxymethyl)propyl](methyl)ami...)
Affinity DataKi:  3.70nMAssay Description:Inhibition of human PNP by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed