BDBM50293054 (R)-N2-(4-Chlorobenzyl)-N2-methyl-N1-[2-methyl-4-(trifluoromethyl)phenyl]pyrrolidine-1,2-dicarboxamide::CHEMBL473734

SMILES CN(Cc1ccc(Cl)cc1)C(=O)[C@H]1CCCN1C(=O)Nc1ccc(cc1C)C(F)(F)F

InChI Key InChIKey=VGKHYFSWFRIGOW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293054   

TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293054((R)-N2-(4-Chlorobenzyl)-N2-methyl-N1-[2-methyl-4-(...)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human CCR1 in THP1 cells assessed as inhibition of MIP-1-alpha-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293054((R)-N2-(4-Chlorobenzyl)-N2-methyl-N1-[2-methyl-4-(...)
Affinity DataIC50: 50nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed