BDBM50293051 (1S)-N1-(4-chlorobenzyl)-N1-methyl-N2-(4-(trifluoromethyl)phenyl)cyclopentane-1,2-dicarboxamide::(R)-N2-(4-Chlorobenzyl)-N2-methyl-N1-[4-(trifluoromethyl)phenyl]pyrrolidine-1,2-dicarboxamide::CHEMBL514611

SMILES CN(Cc1ccc(Cl)cc1)C(=O)[C@H]1CCCN1C(=O)Nc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=QSEJUFNTTKWQER-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50293051   

TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293051((R)-N2-(4-Chlorobenzyl)-N2-methyl-N1-[4-(trifluoro...)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at human CCR1 in THP1 cells assessed as inhibition of MIP-1-alpha-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293051((R)-N2-(4-Chlorobenzyl)-N2-methyl-N1-[4-(trifluoro...)
Affinity DataIC50: 140nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293051((R)-N2-(4-Chlorobenzyl)-N2-methyl-N1-[4-(trifluoro...)
Affinity DataIC50: 140nMAssay Description:Displacement of [125I]-MIP1-alpha from human recombinant CCR1 expressed in HEK293 cells after 4 hrs by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293051((R)-N2-(4-Chlorobenzyl)-N2-methyl-N1-[4-(trifluoro...)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of CCL3-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed