BDBM50290910 CHEMBL4172149

SMILES CCCOc1ccc(NC(=O)NCc2cc(OCC)c(NS(C)(=O)=O)cc2OCC)cc1C(=O)OC

InChI Key InChIKey=IZZJSWADFKQUIR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50290910   

TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50290910(CHEMBL4172149)
Affinity DataIC50: 3.45E+3nMAssay Description:Inhibition of human GST-tagged SHP1 (244 to 570 residues) expressed in Escherichia coli BL21-CondenPlus (DE3) using pNNP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2020
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50290910(CHEMBL4172149)
Affinity DataIC50: 7.76E+3nMAssay Description:Inhibition of human GST-tagged SHP2 (1116 to 2162 residues) expressed in Escherichia coli BL21-CondenPlus (DE3) using pNNP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2020
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50290910(CHEMBL4172149)
Affinity DataIC50: 68nMAssay Description:Inhibition of recombinant human PTP1B using pNNP as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2020
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Qilu University of Technology

Curated by ChEMBL
LigandPNGBDBM50290910(CHEMBL4172149)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of human TCPTP using pNNP as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2020
Entry Details Article
PubMed