BDBM50290838 4-(3-Bromo-phenoxy)-6,7-dimethoxy-quinazoline::CHEMBL98798

SMILES COc1cc2ncnc(Oc3cccc(Br)c3)c2cc1OC

InChI Key InChIKey=BRHOGFZRGDIAMT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50290838   

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290838(4-(3-Bromo-phenoxy)-6,7-dimethoxy-quinazoline | CH...)
Affinity DataIC50: 70nMAssay Description:Inhibition of epidermal growth factor receptor (EGF-R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

LigandPNGBDBM50290838(4-(3-Bromo-phenoxy)-6,7-dimethoxy-quinazoline | CH...)
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290838(4-(3-Bromo-phenoxy)-6,7-dimethoxy-quinazoline | CH...)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of human EGFR-mediated poly(Glu4Tyr) phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50290838(4-(3-Bromo-phenoxy)-6,7-dimethoxy-quinazoline | CH...)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of recombinant human VEGFR-2-mediated poly(Glu4Tyr) phosphorylation after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed