BDBM50290834 4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline::CHEMBL327300

SMILES COc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cc1OC

InChI Key InChIKey=ZQSHUGGLESWJFP-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50290834   

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of epidermal growth factor receptor (EGF-R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetInsulin receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of insulin beta-R in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAPKKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-SRCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetCyclin-dependent kinase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Cdc2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Fibroblast growth factor receptor in NIH 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 130nMAssay Description:Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 30nMAssay Description:Inhibition of Platelet-derived growth factor receptor beta (PDGF beta-R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 70nMAssay Description:Inhibition of platelet-derived growth factor receptor (PDGF-R) from NIH 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Mitogen-activated protein kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 150nMAssay Description:Inhibition of platelet-derived growth factor receptor (PDGF-R) in human aortic smooth muscle cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Protein kinase CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Protein kinase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290834(4-(3,4-Dimethoxy-phenoxy)-6,7-dimethoxy-quinoline ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of epidermal growth factor receptor (EGF-R) in A431 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article