BDBM50290438 (R)-2-Hexyl-N*4*-hydroxy-N*1*-((S)-1-methylcarbamoyl-2-phenyl-ethyl)-succinamide::(R)-2-hexyl-N4-hydroxy-N1-((S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl)succinamide::CHEMBL58945

SMILES CCCCCC[C@H](CC(=O)NO)C(=O)N[C@@H](Cc1ccccc1)C(=O)NC

InChI Key InChIKey=OPPSVVRCTWTXLK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50290438   

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290438((R)-2-hexyl-N4-hydroxy-N1-((S)-1-(methylamino)-1-o...)
Affinity DataIC50: 10nMAssay Description:Compound concentration for 50% inhibition of human recombinant gelatinase A (MMP-2).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290438((R)-2-hexyl-N4-hydroxy-N1-((S)-1-(methylamino)-1-o...)
Affinity DataIC50: 20nMAssay Description:50% inhibition of human recombinant fibroblast collagenase (MMP-1, HFC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290438((R)-2-hexyl-N4-hydroxy-N1-((S)-1-(methylamino)-1-o...)
Affinity DataIC50: 2.00E+3nMAssay Description:50% inhibition of human recombinant MatrilysinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290438((R)-2-hexyl-N4-hydroxy-N1-((S)-1-(methylamino)-1-o...)
Affinity DataIC50: 80nMAssay Description:50% inhibition of human recombinant stromelysin (MMP-3, HFS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290438((R)-2-hexyl-N4-hydroxy-N1-((S)-1-(methylamino)-1-o...)
Affinity DataIC50: 10nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed