BDBM50290188 (2E,4E)-3-Methyl-5-[(1S,2R)-1-methyl-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-cyclopentyl]-penta-2,4-dienoic acid::CHEMBL75814

SMILES C\C(\C=C\[C@]1(C)CCC[C@@H]1c1ccc2c(c1)C(C)(C)CCC2(C)C)=C/C(O)=O

InChI Key InChIKey=FJIBZFRLRGXSSC-UHFFFAOYSA-N

Data  6 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50290188   

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290188((2E,4E)-3-Methyl-5-[(1S,2R)-1-methyl-2-(5,5,8,8-te...)
Affinity DataEC50:  62nMAssay Description:Effective potency in transcriptional activation assay in CV-1 cells expressing Retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetRetinoic acid receptor RXR-beta(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50290188((2E,4E)-3-Methyl-5-[(1S,2R)-1-methyl-2-(5,5,8,8-te...)
Affinity DataEC50:  62nMAssay Description:Effective potency in transcriptional activation assay in CV-1 cells expressing Retinoid X receptor RXR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetRetinoic acid receptor RXR-gamma(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50290188((2E,4E)-3-Methyl-5-[(1S,2R)-1-methyl-2-(5,5,8,8-te...)
Affinity DataEC50:  44nMAssay Description:Effective potency in transcriptional activation assay in CV-1 cells expressing Retinoid X receptor RXR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290188((2E,4E)-3-Methyl-5-[(1S,2R)-1-methyl-2-(5,5,8,8-te...)
Affinity DataKi:  4nMAssay Description:Inhibition of [3H]9-cis-RA binding to Retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetRetinoic acid receptor RXR-gamma(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50290188((2E,4E)-3-Methyl-5-[(1S,2R)-1-methyl-2-(5,5,8,8-te...)
Affinity DataKi:  7nMAssay Description:Inhibition of [3H]9-cis-RA binding to Retinoid X receptor RXR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetRetinoic acid receptor RXR-beta(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50290188((2E,4E)-3-Methyl-5-[(1S,2R)-1-methyl-2-(5,5,8,8-te...)
Affinity DataKi:  10nMAssay Description:Inhibition of [3H]9-cis-RA binding to Retinoid X receptor RXR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetRetinoic acid receptor beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290188((2E,4E)-3-Methyl-5-[(1S,2R)-1-methyl-2-(5,5,8,8-te...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]ATRA binding to retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetRetinoic acid receptor gamma(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290188((2E,4E)-3-Methyl-5-[(1S,2R)-1-methyl-2-(5,5,8,8-te...)
Affinity DataKi: >1.00E+3nMAssay Description:Effective potency in transcriptional activation assay in CV-1 cells expressing retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetRetinoic acid receptor alpha(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290188((2E,4E)-3-Methyl-5-[(1S,2R)-1-methyl-2-(5,5,8,8-te...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]ATRA binding to retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article