BDBM50288508 2-{(R)-1-Benzyl-2-[4-(8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-2-oxo-ethyl}-isoindole-1,3-dione::CHEMBL318189

SMILES Clc1ccc2c(-[#6]-[#6]-c3cccnc3\[#6]-2=[#6]-2\[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#6](=O)-[#6@@H](-[#6]-c2ccccc2)-[#7]-2-[#6](=O)-c3ccccc3-[#6]-2=O)c1

InChI Key InChIKey=RRWFGXHOPIBJBE-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50288508   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
TBA

Curated by ChEMBL

LigandBDBM50288508(2-{(R)-1-Benzyl-2-[4-(8-chloro-5,6-dihydro-benzo[5...)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against protein farnesyltransferase.More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
8/21/2010
Entry Details Article
Copy Entry DOI
Copy Rxn URL