BDBM50288507 CHEMBL318268::[(S)-2-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-1-(4-methoxy-benzylsulfanylmethyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester

SMILES [#6]-[#8]-c1ccc(-[#6]-[#16]-[#6]-[#6@@H](-[#7]-[#6](=O)-[#8]C([#6])([#6])[#6])-[#6](=O)-[#7]-2-[#6]-[#6]\[#6](-[#6]-[#6]-2)=[#6]-2/c3ccc(Cl)cc3-[#6]-[#6]-c3cccnc-23)cc1

InChI Key InChIKey=QYBREFYHMWNFQA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50288507   

LigandPNGBDBM50288507([(S)-2-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohep...)
Affinity DataIC50: 3.05E+3nMAssay Description:Inhibitory activity against protein farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article