BDBM50288506 CHEMBL101603::[(R)-2-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-1-(4-hydroxy-benzyl)-2-oxo-ethyl]-carbamic acid benzyl ester

SMILES [#8]-c1ccc(-[#6]-[#6@@H](-[#7]-[#6](=O)-[#8]-[#6]-c2ccccc2)-[#6](=O)-[#7]-2-[#6]-[#6]\[#6](-[#6]-[#6]-2)=[#6]-2\c3ccc(Cl)cc3-[#6]-[#6]-c3cccnc-23)cc1

InChI Key InChIKey=OHVVBEYDIQLHIP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50288506   

LigandPNGBDBM50288506([(R)-2-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohep...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory activity against protein farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article