BDBM50288505 (R)-5-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-5-oxo-pentanoic acid phenylamide::CHEMBL327507

SMILES Clc1ccc2c(-[#6]-[#6]-c3cccnc3\[#6]-2=[#6]-2\[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#6](=O)-[#6@@H](-[#6]-[#6]-[#6](=O)-[#7]-c2ccccc2)-[#7]-2-[#6](=O)-c3ccccc3-[#6]-2=O)c1

InChI Key InChIKey=MMKCWQLDHMKHHD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50288505   

LigandPNGBDBM50288505((R)-5-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohept...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibitory activity against protein farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article