BDBM50288501 2-{2-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-2-oxo-ethyl}-isoindole-1,3-dione::CHEMBL100302

SMILES Clc1ccc2c(-[#6]-[#6]-c3cccnc3\[#6]-2=[#6]-2\[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#6](=O)-[#6]-[#7]-2-[#6](=O)-c3ccccc3-[#6]-2=O)c1

InChI Key InChIKey=OGNDWKHVENKNOI-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50288501   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
TBA

Curated by ChEMBL

LigandBDBM50288501(2-{2-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta...)Copy SMILESCopy InChI

Affinity DataIC50: 660nMAssay Description:Inhibitory activity against protein farnesyltransferase.More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
8/21/2010
Entry Details Article
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