BDBM50288493 CHEMBL323298::{2-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-2-oxo-ethyl}-carbamic acid tert-butyl ester

SMILES [#6]C([#6])([#6])[#8]-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1\c2ccc(Cl)cc2-[#6]-[#6]-c2cccnc-12

InChI Key InChIKey=ZOVCGIRMLOACDT-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50288493   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
TBA

Curated by ChEMBL

LigandBDBM50288493({2-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1...)Copy SMILESCopy InChI

Affinity DataIC50: 6.80E+3nMAssay Description:Inhibitory activity against protein farnesyltransferase.More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
8/21/2010
Entry Details Article
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