BDBM50288408 1-(3-Phenyl-propionyl)-pyrrolidine-2-carboxylic acid (5-amino-1-dihydroxyboranyl-pentyl)-amide::CHEMBL320897

SMILES NCCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)CCc1ccccc1)B(O)O

InChI Key InChIKey=UOMOHVALINFUIP-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50288408   

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288408(CHEMBL320897 | 1-(3-Phenyl-propionyl)-pyrrolidine-...)
Affinity DataKi:  0.800nMAssay Description:Compound was evaluated for the inhibitory activity against thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288408(CHEMBL320897 | 1-(3-Phenyl-propionyl)-pyrrolidine-...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity to human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288408(CHEMBL320897 | 1-(3-Phenyl-propionyl)-pyrrolidine-...)
Affinity DataKi:  0.800nMAssay Description:In vitro for inhibition of thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProthrombin(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50288408(CHEMBL320897 | 1-(3-Phenyl-propionyl)-pyrrolidine-...)
Affinity DataKi:  100nMAssay Description:Concentration necessary to double time for clot formation induced by bovine thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article