BDBM50288403 CHEMBL330206::N-[(5-Amino-1-dihydroxyboranyl-pentylcarbamoyl)-methyl]-N-isopropyl-3-phenyl-propionamide

SMILES CC(C)N(CC(=O)N[C@@H](CCCCN)B(O)O)C(=O)CCc1ccccc1

InChI Key InChIKey=MBPIOWHYJVTSDB-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50288403   

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288403(N-[(5-Amino-1-dihydroxyboranyl-pentylcarbamoyl)-me...)
Affinity DataKi:  1.60nMAssay Description:In vitro for inhibition of thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetSerine protease 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288403(N-[(5-Amino-1-dihydroxyboranyl-pentylcarbamoyl)-me...)
Affinity DataKi:  3.80nMAssay Description:Compound was tested in vitro for inhibition of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProthrombin(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50288403(N-[(5-Amino-1-dihydroxyboranyl-pentylcarbamoyl)-me...)
Affinity DataKi:  125nMAssay Description:Concentration necessary to double time for clot formation induced by bovine thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetPlasminogen(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288403(N-[(5-Amino-1-dihydroxyboranyl-pentylcarbamoyl)-me...)
Affinity DataKi:  140nMAssay Description:In vitro for inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetTissue-type plasminogen activator(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288403(N-[(5-Amino-1-dihydroxyboranyl-pentylcarbamoyl)-me...)
Affinity DataKi:  3.37E+3nMAssay Description:Compound was tested in vitro for inhibition of tissue plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article