BDBM50287764 17-ethyl-1,14-dihydroxy-22,24-dimethoxy-12-[2-[3-methoxy-4-(2-naphthyloxy)cyclohexyl]-1-methyl-(E)-1-ethenyl]-13,19,21,26-tetramethyl-(23S)-11,27-dioxa-4-azatricyclo[21.3.1.04,9]heptacos-18-ene-2,3,10,16-tetraone::CHEMBL302040

SMILES CC[C@@H]1\C=C(C)\C[C@H](C)[C@H](OC)[C@H]2O[C@](O)([C@H](C)C[C@@H]2OC)C(=O)C(=O)N2CCCC[C@H]2C(=O)O[C@@H]([C@H](C)[C@@H](O)CC1=O)C(\C)=C\[C@@H]1CC[C@@H](Oc2ccc3ccccc3c2)[C@@H](C1)OC

InChI Key InChIKey=HXQBZJPBECLXEL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50287764   

LigandPNGBDBM50287764(17-ethyl-1,14-dihydroxy-22,24-dimethoxy-12-[2-[3-m...)
Affinity DataIC50: 75nMAssay Description:In vitro competitive binding to FK506 binding protein 12 versus tritiated FK-506.More data for this Ligand-Target Pair
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Date in BDB:
8/21/2010
Entry Details Article