BDBM50287550 5-(2-ethoxy-5-(4-(2-hydroxyethyl)piperazin-1-ylsulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one::5-{2-Ethoxy-5-[4-(2-hydroxy-ethyl)-piperazine-1-sulfonyl]-phenyl}-1-methyl-3-propyl-1,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one::CHEMBL53538

SMILES CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(CCO)CC1

InChI Key InChIKey=NEYKRKVLEWKOBI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50287550   

LigandPNGBDBM50287550(5-{2-Ethoxy-5-[4-(2-hydroxy-ethyl)-piperazine-1-su...)
Affinity DataIC50: 19nMAssay Description:Inhibition of Phosphodiesterase 5 from human corpus cavernosumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

LigandPNGBDBM50287550(5-{2-Ethoxy-5-[4-(2-hydroxy-ethyl)-piperazine-1-su...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
LigandPNGBDBM50287550(5-{2-Ethoxy-5-[4-(2-hydroxy-ethyl)-piperazine-1-su...)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of Phosphodiesterase 3 from rabbit plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

LigandPNGBDBM50287550(5-{2-Ethoxy-5-[4-(2-hydroxy-ethyl)-piperazine-1-su...)
Affinity DataIC50: 460nMAssay Description:Inhibition of Phosphodiesterase 1 from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article