BDBM50287521 CHEMBL2146753

SMILES [O-][N+](=O)c1ccc2nc(COCc3nc4ccc(cc4[nH]3)[N+]([O-])=O)[nH]c2c1

InChI Key InChIKey=ZQPXNYLXYNRFNP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50287521   

LigandPNGBDBM50287521(CHEMBL2146753)
Affinity DataIC50: 398nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
LigandPNGBDBM50287521(CHEMBL2146753)
Affinity DataIC50: 794nMAssay Description:Inhibition of human ROMK1 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
LigandPNGBDBM50287521(CHEMBL2146753)
Affinity DataIC50: 420nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
LigandPNGBDBM50287521(CHEMBL2146753)
Affinity DataIC50: 744nMAssay Description:Inhibition of human ROMK1 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
LigandPNGBDBM50287521(CHEMBL2146753)
Affinity DataIC50: 240nMAssay Description:Inhibition of rat ROMK1 expressed in HEK293 cells by Tl+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed