BDBM50287511 1-Cyclohexyl-3-(2,6-diisopropyl-phenyl)-1-(2-dodecyl-2H-tetrazol-5-yl)-urea::CHEMBL49639

SMILES CCCCCCCCCCCCn1nnc(n1)N(C1CCCCC1)C(=O)Nc1c(cccc1C(C)C)C(C)C

InChI Key InChIKey=BXKJJEHNPZBTMN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50287511   

TargetSterol O-acyltransferase 1(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50287511(1-Cyclohexyl-3-(2,6-diisopropyl-phenyl)-1-(2-dodec...)
Affinity DataIC50: 3.10E+3nMAssay Description:Compound was tested for its ability to penetrate the cell wall and inhibit macrophage ACAT in cell culture using murine IC-21 macrophages (MAI)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50287511(1-Cyclohexyl-3-(2,6-diisopropyl-phenyl)-1-(2-dodec...)
Affinity DataIC50: 31nMAssay Description:Liver Acyl coenzyme A:cholesterol acyltransferase inhibitory activity was determined in vitro using [1-14C]oleolyl-CoA and microsomes isolated from t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article