BDBM50287426 CHEMBL41057::[(2R,4S)-2-Benzyl-1-(3,5-bis-trifluoromethyl-benzyl)-piperidin-4-yl]-quinolin-4-ylmethyl-amine

SMILES FC(F)(F)c1cc(CN2CC[C@@H](C[C@H]2Cc2ccccc2)NCc2ccnc3ccccc23)cc(c1)C(F)(F)F

InChI Key InChIKey=KCHZSHRRZWMRFQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50287426   

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287426([(2R,4S)-2-Benzyl-1-(3,5-bis-trifluoromethyl-benzy...)
Affinity DataIC50: 880nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article