BDBM50287323 3-{2-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-isopropyl-1H-indol-2-yl]-1,1-dimethyl-ethyl}-1-hydroxy-1-methyl-urea::CHEMBL290170

SMILES CC(C)c1ccc2n(Cc3ccc(Cl)cc3)c(CC(C)(C)NC(=O)N(C)O)c(SC(C)(C)C)c2c1

InChI Key InChIKey=JLKPDXDVZIAJLR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50287323   

LigandPNGBDBM50287323(3-{2-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-i...)
Affinity DataIC50: 7.50E+3nMAssay Description:Compound was tested for inhibition of 5-lipoxygenase activity in a broken cell supernatant rat basophilic leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

LigandPNGBDBM50287323(3-{2-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-i...)
Affinity DataIC50: 150nMAssay Description:Inhibition of calcium ionophore (A23187) stimulated LTB4 formation in human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

LigandPNGBDBM50287323(3-{2-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-i...)
Affinity DataIC50: 1.30E+3nMAssay Description:Human whole blood was stimulated with calcium ionophore (A23187) and LTB 4 measured by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article