BDBM50287173 4-Chloro-1-methoxy-naphthalene-2-carboxylic acid [2-(4-phenyl-piperazin-1-yl)-ethyl]-amide::CHEMBL416939

SMILES COc1c(cc(Cl)c2ccccc12)C(=O)NCCN1CCN(CC1)c1ccccc1

InChI Key InChIKey=ARZYDJJAHRASCM-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50287173   

TargetD(3) dopamine receptor(Human)
University Centre For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50287173(4-Chloro-1-methoxy-naphthalene-2-carboxylic acid [...)
Affinity DataKi:  50.1nMAssay Description:Competitive inhibition of [3H]spiperone binding to the human dopamine receptor D3 expressed in CHO cells, expressed as 10log KiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University Centre For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50287173(4-Chloro-1-methoxy-naphthalene-2-carboxylic acid [...)
Affinity DataKi:  55nMAssay Description:Binding affinity at Dopamine D3 receptors in rat striatum by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287173(4-Chloro-1-methoxy-naphthalene-2-carboxylic acid [...)
Affinity DataKi:  2.53E+3nMAssay Description:Binding affinity at Dopamine D2 receptors in rat striatum by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article