BDBM50287165 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid [2-(4-o-tolyl-piperazin-1-yl)-ethyl]-amide::CHEMBL28964

SMILES COc1c(cc(Br)c2ccccc12)C(=O)NCCN1CCN(CC1)c1ccccc1C

InChI Key InChIKey=ZIVBQUNYSGOUKO-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50287165   

TargetD(3) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287165(4-Bromo-1-methoxy-naphthalene-2-carboxylic acid [2...)
Affinity DataEC50: >1.00E+3nMAssay Description:Stimulation of mitogenesis in Dopamine receptor D3 transfected CHO p-5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetD(3) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287165(4-Bromo-1-methoxy-naphthalene-2-carboxylic acid [2...)
Affinity DataKi:  63.1nMAssay Description:Competitive inhibition of [3H]spiperone binding to the human dopamine receptor D3 expressed in CHO cells, expressed as 10log KiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287165(4-Bromo-1-methoxy-naphthalene-2-carboxylic acid [2...)
Affinity DataKi:  66nMAssay Description:Binding affinity at Dopamine D3 receptors in rat striatum by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287165(4-Bromo-1-methoxy-naphthalene-2-carboxylic acid [2...)
Affinity DataKi:  484nMAssay Description:Binding affinity at Dopamine D2 receptors in rat striatum by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article