BDBM50287089 CHEMBL278287::N-Methyl-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide

SMILES CN(C(=O)c1ccccc1)c1ccc(C)c(Nc2nccc(n2)-c2cccnc2)c1

InChI Key InChIKey=HTCQGVPSEDIYST-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50287089   

TargetProtein kinase C alpha type(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287089(N-Methyl-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2...)
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of serine/threonine kinase(PKC-alpha)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287089(N-Methyl-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2...)
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of tyrosine kinase Epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetProtein kinase C delta type(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287089(N-Methyl-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of serine/threonine kinase(PKC-delta)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

LigandPNGBDBM50287089(N-Methyl-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of tyrosine kinase(PDGF-R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

LigandPNGBDBM50287089(N-Methyl-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of serine/threonine kinase(PKA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article