BDBM50285588 CHEMBL4171224

SMILES CC[C@H]1N(C2CCCC2)c2nc(ncc2N(C)C1=O)-n1ccc2cc(ccc12)C(=O)NCC(C)C

InChI Key InChIKey=MCJYLZXJWVLMLI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50285588   

TargetSerine/threonine-protein kinase PLK1(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50285588(CHEMBL4171224)
Affinity DataIC50: 122nMAssay Description:Inhibition human recombinant full length His-tagged Plk1 expressed in baculovirus expression system after 1 hr by FRET-based Z'-Lyte assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50285588(CHEMBL4171224)
Affinity DataIC50: 2.79E+3nMAssay Description:Inhibition human recombinant GST-tagged Plk3 catalytic domain (58 to 340 residues) expressed in baculovirus expression system after 1 hr by FRET-base...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PLK2(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50285588(CHEMBL4171224)
Affinity DataIC50: 19nMAssay Description:Inhibition human recombinant full length GST-tagged Plk2 expressed in baculovirus expression system after 1 hr by FRET-based Z'-Lyte assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed