BDBM50285537 CHEMBL4166771

SMILES CC[C@H]1N(C2CCCC2)c2nc(Nc3ccc(cc3)S(=O)(=O)NC)ncc2N(C)C1=O

InChI Key InChIKey=PRMNYSLMFFRETJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50285537   

TargetSerine/threonine-protein kinase PLK2(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50285537(CHEMBL4166771)
Affinity DataIC50: 3.40nMAssay Description:Inhibition human recombinant full length GST-tagged Plk2 expressed in baculovirus expression system after 1 hr by FRET-based Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50285537(CHEMBL4166771)
Affinity DataIC50: 16nMAssay Description:Inhibition human recombinant full length His-tagged Plk1 expressed in baculovirus expression system after 1 hr by FRET-based Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50285537(CHEMBL4166771)
Affinity DataIC50: 39nMAssay Description:Inhibition human recombinant GST-tagged Plk3 catalytic domain (58 to 340 residues) expressed in baculovirus expression system after 1 hr by FRET-base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2020
Entry Details Article
PubMed