BDBM50284495 4-[5-(4-Fluoro-phenyl)-2-(4-methanesulfinyl-phenyl)-3H-imidazol-4-yl]-quinoline::CHEMBL16911

SMILES CS(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc2ccccc12

InChI Key InChIKey=RXGCJIGYVLKTIO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50284495   

LigandPNGBDBM50284495(CHEMBL16911 | 4-[5-(4-Fluoro-phenyl)-2-(4-methanes...)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibitory activity against 5-lipoxygenase enzyme from RBL-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50284495(CHEMBL16911 | 4-[5-(4-Fluoro-phenyl)-2-(4-methanes...)
Affinity DataIC50: 710nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article