BDBM50284224 6-Methoxy-9-pyridin-2-ylmethyl-1,9-dihydro-[1,3]oxazino[4,5-b]indole-2,4-dione::CHEMBL354406

SMILES COc1ccc2n(Cc3ccccn3)c3nc(=O)oc(O)c3c2c1

InChI Key InChIKey=ZXVRTHNEVCBHPW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50284224   

TargetNeutrophil elastase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284224(6-Methoxy-9-pyridin-2-ylmethyl-1,9-dihydro-[1,3]ox...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory activity against human leukocyte elastase using MeO-Suc-Ala-Ala-Pro-Val-pNA (416 uM) as substrate;No InhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetChymotrypsinogen A(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50284224(6-Methoxy-9-pyridin-2-ylmethyl-1,9-dihydro-[1,3]ox...)
Affinity DataIC50: 5.12E+5nMAssay Description:Inhibitory activity against chymotrypsin using Suc-Ala-Ala-Pro-Phe-pNA (416 uM) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article