BDBM50283875 CHEMBL98055::N-Cyclohexylmethyl-N'-(ethoxy-hydroxy-methyl)-N''-[3-(1H-imidazol-4-yl)-propyl]-guanidine

SMILES CCOC(=O)NC(NCCCc1cnc[nH]1)=NCC1CCCCC1

InChI Key InChIKey=KCJHHQPEKNEXFB-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50283875   

TargetHistamine H3 receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50283875(N-Cyclohexylmethyl-N'-(ethoxy-hydroxy-methyl)-N''-...)
Affinity DataKi:  36nMAssay Description:Antagonistic activity for Histamine H3 receptor binding in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetHistamine H3 receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50283875(N-Cyclohexylmethyl-N'-(ethoxy-hydroxy-methyl)-N''-...)
Affinity DataKi:  39.8nMAssay Description:Antagonistic activity for Histamine H3 receptor on electrically evoked guinea-pig ileum contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article