BDBM50283763 CHEMBL321531::N-(3-{3-Butyl-4-[2'-(2-chloro-benzoylsulfamoyl)-3-fluoro-5'-propyl-biphenyl-4-ylmethyl]-5-oxo-4,5-dihydro-[1,2,4]triazol-1-yl}-4-chloro-phenyl)-acetamide

SMILES CCCCc1nn(-c2cc(NC(C)=O)ccc2Cl)c(=O)n1Cc1ccc(cc1F)-c1cc(CCC)ccc1S(=O)(=O)NC(=O)c1ccccc1Cl

InChI Key InChIKey=IOTNAIBDHBSLIU-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50283763   

TargetType-2 angiotensin II receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283763(N-(3-{3-Butyl-4-[2'-(2-chloro-benzoylsulfamoyl)-3-...)
Affinity DataIC50: 0.480nMAssay Description:Inhibitory concentration against cloned human AT1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetType-1 angiotensin II receptor(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50283763(N-(3-{3-Butyl-4-[2'-(2-chloro-benzoylsulfamoyl)-3-...)
Affinity DataIC50: 0.900nMAssay Description:In vitro ability to inhibit the binding of radioligand 125I[Sar1,IIe8]AII to AT1 receptor from rabbit aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetType-1 angiotensin II receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283763(N-(3-{3-Butyl-4-[2'-(2-chloro-benzoylsulfamoyl)-3-...)
Affinity DataIC50: 16nMAssay Description:In vitro inhibitory concentration against AT1 receptor from human adrenal tissues.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetType-2 angiotensin II receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283763(N-(3-{3-Butyl-4-[2'-(2-chloro-benzoylsulfamoyl)-3-...)
Affinity DataIC50: 0.150nMAssay Description:Inhibitory concentration against AT2 receptor from rat adrenal tissues.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50283763(N-(3-{3-Butyl-4-[2'-(2-chloro-benzoylsulfamoyl)-3-...)
Affinity DataIC50: 0.380nMAssay Description:Inhibitory concentration against AT1 receptor from rat adrenal tissues.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetType-2 angiotensin II receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283763(N-(3-{3-Butyl-4-[2'-(2-chloro-benzoylsulfamoyl)-3-...)
Affinity DataIC50: 17nMAssay Description:In vitro inhibitory concentration against AT2 receptor from human adrenal tissues.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetType-2 angiotensin II receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283763(N-(3-{3-Butyl-4-[2'-(2-chloro-benzoylsulfamoyl)-3-...)
Affinity DataIC50: 0.110nMAssay Description:Inhibitory concentration against AT1 receptor from rat adrenal tissuesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article