BDBM50283033 CHEMBL4160854

SMILES Nc1n[nH]c2cccc(-c3ccc(NC(=S)Nc4cc(Br)ccc4OC(F)(F)F)cc3)c12

InChI Key InChIKey=DSRUNANRDDLTEB-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50283033   

TargetVascular endothelial growth factor receptor 3(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50283033(CHEMBL4160854)
Affinity DataIC50: 37nMAssay Description:Inhibition of VEGFR3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2020
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 4(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50283033(CHEMBL4160854)
Affinity DataIC50: 866nMAssay Description:Inhibition of FGFR4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2020
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50283033(CHEMBL4160854)
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of c-KIT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2020
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50283033(CHEMBL4160854)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of TIE2 (unknown origin) after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50283033(CHEMBL4160854)
Affinity DataIC50: 23nMAssay Description:Inhibition of VEGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50283033(CHEMBL4160854)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2020
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50283033(CHEMBL4160854)
Affinity DataIC50: 167nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50283033(CHEMBL4160854)
Affinity DataIC50: 177nMAssay Description:Inhibition of PDGFRbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2020
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50283033(CHEMBL4160854)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of IGF1R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50283033(CHEMBL4160854)
Affinity DataIC50: 20nMAssay Description:Inhibition of BRAF (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2020
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50283033(CHEMBL4160854)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-MET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50283033(CHEMBL4160854)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of VEGFR2 (unknown origin) using Poly E4Y1 substrate after 1 hr by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2020
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50283033(CHEMBL4160854)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of EPHB4 (unknown origin) after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2020
Entry Details Article
PubMed