BDBM50282650 CHEMBL4173207

SMILES CC(C(=O)Nc1ncccc1C)c1ccc(Nc2ccnc(c2)C(F)(F)F)cc1

InChI Key InChIKey=OIIKNDIDIVAIBV-UHFFFAOYSA-N

Data  2 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50282650   

TargetFatty-acid amide hydrolase 1(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50282650(CHEMBL4173207)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of FAAH T488A mutant (unknown origin) expressed in human HeLa cells using [3H]AEA as substrate after 2 hrs by liquid scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50282650(CHEMBL4173207)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of FAAH (unknown origin) expressed in human HeLa cells transfected with empty vector using [3H]AEA as substrate after 2 hrs by liquid scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50282650(CHEMBL4173207)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of FAAH (unknown origin) expressed in human HeLa cells using [3H]AEA as substrate after 2 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50282650(CHEMBL4173207)
Affinity DataIC50: 590nMAssay Description:Inhibition of rat brain FAAH using [3H]AEA as substrate after 10 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50282650(CHEMBL4173207)
Affinity DataIC50: 589nMAssay Description:Inhibition of rat brain FAAH using [3H]AEA as substrate after 10 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50282650(CHEMBL4173207)
Affinity DataKi:  390nMAssay Description:Competitive inhibition of rat brain FAAH using [3H]AEA as substrate after 10 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Mouse)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50282650(CHEMBL4173207)
Affinity DataKi:  6.30E+3nMAssay Description:Mixed-type inhibition of B6CBAF1/J mouse brain FAAH using [3H]AEA as substrate after 10 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2020
Entry Details Article
PubMed