BDBM50282361 4'-(2-Ethyl-6,8-dimethyl-imidazo[1,2-b]pyridazin-3-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL71730

SMILES CCc1nc2c(C)cc(C)nn2c1Cc1ccc(cc1)-c1ccccc1C(O)=O

InChI Key InChIKey=ROUFBOJBHYIEPP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50282361   

TargetType-1 angiotensin II receptor(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50282361(4'-(2-Ethyl-6,8-dimethyl-imidazo[1,2-b]pyridazin-3...)
Affinity DataIC50: 83nMAssay Description:In vitro binding affinity evaluated by its ability to displace the specific binding ligand 125I-SAR1, Ile8-AII from Angiotensin II receptor, type 1 i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetType-2 angiotensin II receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282361(4'-(2-Ethyl-6,8-dimethyl-imidazo[1,2-b]pyridazin-3...)
Affinity DataIC50: 10nMAssay Description:In vitro binding affinity to AT2 receptor determined by its ability to displace the specific binding ligand [125I]-Sar1, Ile8-AII from AT2 receptor i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article