BDBM50282226 CHEMBL4160694

SMILES OC1C(Br)=CC2(C=CNC3=C2C2=NCCc4c[nH]c(c24)C3=O)C=C1Br

InChI Key InChIKey=VWVMXLKFSHMROH-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50282226   

TargetAcetylcholinesterase(Electric eel)
University of Maribor

Curated by ChEMBL
LigandPNGBDBM50282226(CHEMBL4160694)
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured over 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Maribor

Curated by ChEMBL
LigandPNGBDBM50282226(CHEMBL4160694)
Affinity DataIC50: 1.52E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate measured over 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2020
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Maribor

Curated by ChEMBL
LigandPNGBDBM50282226(CHEMBL4160694)
Affinity DataIC50: 1.58E+4nMAssay Description:Reversible competitive inhibition of equine serum BChE using acetylthiocholine iodide as substrate measured over 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Maribor

Curated by ChEMBL
LigandPNGBDBM50282226(CHEMBL4160694)
Affinity DataKi:  3.50E+3nMAssay Description:Reversible competitive inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured over 5 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2020
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Maribor

Curated by ChEMBL
LigandPNGBDBM50282226(CHEMBL4160694)
Affinity DataKi:  1.75E+4nMAssay Description:Inhibition of equine serum BChE using acetylthiocholine iodide as substrate measured over 5 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Maribor

Curated by ChEMBL
LigandPNGBDBM50282226(CHEMBL4160694)
Affinity DataKi:  9.80E+4nMAssay Description:Reversible competitive inhibition of human AChE using acetylthiocholine iodide as substrate measured over 5 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2020
Entry Details Article
PubMed