BDBM50282163 CHEMBL4171889

SMILES [H][C@]12C[C@H](N[C@@]1([H])CCCC2)C(=O)N[C@@H](CCCCN(C)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(N)=O

InChI Key InChIKey=QCOPPCLMRKMEKM-UHFFFAOYSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50282163   

TargetPolycomb protein EED(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50282163(CHEMBL4171889)
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of full length N-terminal His-tagged EED (unknown origin) expressed in Rosetta2 BL21(DE3)pLysS cells after 30 mins by 3-FAM labelled fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50282163(CHEMBL4171889)
Affinity DataKd:  680nMAssay Description:Binding affinity to full length N-terminal His-tagged EED (unknown origin) expressed in Rosetta2 BL21(DE3)pLysS cells by ITC methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50282163(CHEMBL4171889)
Affinity DataIC50: 1.70E+3nMAssay Description:Displacement of 3-FAM from N-terminal 6His-tagged full length EED (unknown origin) expressed in Escherichia coli Rosetta2 BL21(DE3)pLysS incubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolycomb protein EED(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50282163(CHEMBL4171889)
Affinity DataKd:  680nMAssay Description:Binding affinity to N-terminal His-tagged full length EED (unknown origin) by ITC methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed