BDBM50281425 3-(4-Fluoro-phenyl)-8-methyl-1-oxa-8-aza-spiro[4.5]dec-2-en-4-one; hydrochloride::CHEMBL555900

SMILES CN1CCC2(CC1)OC=C(C2=O)c1ccc(F)cc1

InChI Key InChIKey=PKZJUJBTXBROLF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50281425   

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50281425(3-(4-Fluoro-phenyl)-8-methyl-1-oxa-8-aza-spiro[4.5...)
Affinity DataKi:  2.60E+3nMAssay Description:Binding affinity for dopamine receptor D2 in guinea pig striatal membrane using radiolabeled ligand [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50281425(3-(4-Fluoro-phenyl)-8-methyl-1-oxa-8-aza-spiro[4.5...)
Affinity DataKi:  4.00E+3nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article