BDBM50281416 2-(4-Methoxy-phenyl)-8-phenethyl-1-oxa-8-aza-spiro[4.5]dec-2-en-4-one; hydrochloride::CHEMBL543591

SMILES COc1ccc(cc1)C1=CC(=O)C2(CCN(CCc3ccccc3)CC2)O1

InChI Key InChIKey=OZNIIAAKDSMLHL-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50281416   

LigandPNGBDBM50281416(2-(4-Methoxy-phenyl)-8-phenethyl-1-oxa-8-aza-spiro...)
Affinity DataKi:  26nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50281416(2-(4-Methoxy-phenyl)-8-phenethyl-1-oxa-8-aza-spiro...)
Affinity DataKi:  8.40E+3nMAssay Description:Binding affinity for dopamine receptor D2 in guinea pig striatal membrane using radiolabeled ligand [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article