BDBM50281411 8-Benzyl-3-(4-fluoro-phenyl)-1-oxa-8-aza-spiro[4.5]decan-4-one; hydrochloride::8-Benzyl-3-(4-fluoro-phenyl)-3-methyl-1-oxa-8-aza-spiro[4.5]decan-4-one; hydrochloride::CHEMBL543344

SMILES Fc1ccc(cc1)C1COC2(CCN(Cc3ccccc3)CC2)C1=O

InChI Key InChIKey=LQRUHPTVKTXHPR-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50281411   

LigandPNGBDBM50281411(8-Benzyl-3-(4-fluoro-phenyl)-3-methyl-1-oxa-8-aza-...)
Affinity DataKi:  4nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50281411(8-Benzyl-3-(4-fluoro-phenyl)-3-methyl-1-oxa-8-aza-...)
Affinity DataKi:  4nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-SKF- 10,047More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50281411(8-Benzyl-3-(4-fluoro-phenyl)-3-methyl-1-oxa-8-aza-...)
Affinity DataKi:  47nMAssay Description:Binding affinity for dopamine receptor D2 in guinea pig striatal membrane using radiolabeled ligand [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50281411(8-Benzyl-3-(4-fluoro-phenyl)-3-methyl-1-oxa-8-aza-...)
Affinity DataKi:  47nMAssay Description:Binding affinity towards dopamine D2 receptor using radiolabeled ligand [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article