BDBM50281173 CHEMBL4169359::US12162877, Compound 7

SMILES Cn1n2ccccc2c(C(=O)Nc2c(F)c(F)c(c(F)c2F)-c2ccccc2)c1=O

InChI Key InChIKey=MUTGDOHUSOREOS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50281173   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50281173(CHEMBL4169359 | US12162877, Compound 7)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human DHODH (31 to 395 residues) expressed in Escherichia coli BL21(DE3) assessed as inhibition of DC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2020
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50281173(CHEMBL4169359 | US12162877, Compound 7)
Affinity DataIC50: 5.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2025
Entry Details
Go to US Patent