BDBM50281039 (2S,5S,6S)-6-Acetoxy-3,3-dimethyl-4,7-dioxo-4lambda*4*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzyl ester::CHEMBL307225

SMILES CC(=O)O[C@@H]1[C@H]2N([C@@H](C(=O)OCc3ccccc3)C(C)(C)S2=O)C1=O

InChI Key InChIKey=GJWYCXZNJCDYTB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50281039   

TargetNeutrophil elastase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50281039((2S,5S,6S)-6-Acetoxy-3,3-dimethyl-4,7-dioxo-4lambd...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory concentration required against Human Leukocyte Elastase (HLE) for 50% reduction in rate of hydrolysis of (suc-Ala-Ala-Pro-Ala-p-NA) peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article