BDBM50281031 (2S,5R,6S)-6-Chloro-3,3-dimethyl-4,4,7-trioxo-4lambda*6*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzyl ester::CHEMBL302630

SMILES CC1(C)[C@@H](N2[C@@H]([C@@H](Cl)C2=O)S1(=O)=O)C(=O)OCc1ccccc1

InChI Key InChIKey=NPUNVIPJUAMQEM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50281031   

TargetNeutrophil elastase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50281031((2S,5R,6S)-6-Chloro-3,3-dimethyl-4,4,7-trioxo-4lam...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibitory concentration required against Human Leukocyte Elastase (HLE) for 50% reduction in rate of hydrolysis of (suc-Ala-Ala-Pro-Ala-p-NA) peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetNeutrophil elastase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50281031((2S,5R,6S)-6-Chloro-3,3-dimethyl-4,4,7-trioxo-4lam...)
Affinity DataIC50: 1.40E+4nMAssay Description:Compound was tested in vitro for its ability to inhibit human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50281031((2S,5R,6S)-6-Chloro-3,3-dimethyl-4,4,7-trioxo-4lam...)
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibition of porcine Pancreatic elastase without pre-incubationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50281031((2S,5R,6S)-6-Chloro-3,3-dimethyl-4,4,7-trioxo-4lam...)
Affinity DataIC50: 2.05E+5nMAssay Description:Inhibition of porcine Pancreatic elastase without pre-incubationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article