BDBM50281026 (2S,5R,6S)-6-(1-Hydroxy-ethyl)-3,3-dimethyl-4,4,7-trioxo-4lambda*6*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzyl ester::CHEMBL74648

SMILES CC(O)[C@@H]1[C@@H]2N([C@@H](C(=O)OCc3ccccc3)C(C)(C)S2(=O)=O)C1=O

InChI Key InChIKey=JHVPJZBVOQEORX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50281026   

TargetNeutrophil elastase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50281026((2S,5R,6S)-6-(1-Hydroxy-ethyl)-3,3-dimethyl-4,4,7-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory concentration required against Human Leukocyte Elastase (HLE) for 50% reduction in rate of hydrolysis of (suc-Ala-Ala-Pro-Ala-p-NA) peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article