BDBM50280830 3-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-1H-quinazoline-2,4-dione::CHEMBL300585

SMILES Fc1ccc2[nH]cc(CC3CCN(CCn4c(=O)[nH]c5ccccc5c4=O)CC3)c2c1

InChI Key InChIKey=OIYZVNIQJKHCEA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50280830   

TargetD(2) dopamine receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50280830(3-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: 100nMAssay Description:Tested for its binding affinity against Dopamine receptor D2; showed no appreciable affinity at concentration specifiedMore data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50280830(3-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: 100nMAssay Description:Tested for its binding affinity against Alpha-1 adrenergic receptor; showed no appreciable affinity at concentration specifiedMore data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50280830(3-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: 100nMAssay Description:Tested for its binding affinity against muscarinic receptor; showed no appreciable affinity at concentration specifiedMore data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50280830(3-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: 0.5nMAssay Description:Compound was evaluated for inhibition of 5-HT uptake by measuring its ability to inhibit [3H]paroxetine binding to rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails Article