BDBM50280811 5-[(1R,2S)-2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-propyl]-1,3-dihydro-indol-2-one::CHEMBL172807

SMILES C[C@@H]([C@H](O)c1ccc2NC(=O)Cc2c1)N1CCC(Cc2ccccc2)CC1

InChI Key InChIKey=FCXXSNGUDWIOQU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50280811   

LigandPNGBDBM50280811(5-[(1R,2S)-2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-p...)
Affinity DataIC50: 231nMAssay Description:Tested for the NMDA antagonist activity using a functional assay, by protection of cultured hippocampus neurons from the toxic effects of extracellul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280811(5-[(1R,2S)-2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-p...)
Affinity DataIC50: 100nMAssay Description:Tested for the Alpha-1 adrenergic receptor affinity in a standard radioligand binding assay with [3H]- prazosinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article