BDBM50280301 (2R,3R,4S)-2-(6-Amino-purin-9-yl)-5-[1-fluoro-meth-(E)-ylidene]-tetrahydro-furan-3,4-diol::CHEMBL297437

SMILES Nc1ncnc2n(cnc12)[C@@H]1O\C(=C\F)[C@@H](O)[C@H]1O

InChI Key InChIKey=NAWIFPQLACUTSO-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50280301   

TargetAdenosylhomocysteinase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50280301((2R,3R,4S)-2-(6-Amino-purin-9-yl)-5-[1-fluoro-meth...)
Affinity DataKi:  40nMAssay Description:Compound was tested for its inhibitory activity against recombinant rat liver S-adenosyl-homocysteine hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetAdenosylhomocysteinase(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50280301((2R,3R,4S)-2-(6-Amino-purin-9-yl)-5-[1-fluoro-meth...)
Affinity DataKi:  1.04E+3nMAssay Description:Activity determined in mouse liver S-adenosyl-L-homocysteine hydrolase and expressed as KI values.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetAdenosylhomocysteinase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50280301((2R,3R,4S)-2-(6-Amino-purin-9-yl)-5-[1-fluoro-meth...)
Affinity DataKi:  2.40E+3nMAssay Description:Competitive inhibitory activity against rat liver S-Adenosyl-homocysteine hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed