BDBM50280101 CHEMBL4061296

SMILES Oc1ccc(cc1)-c1ccc2cn[nH]c2c1

InChI Key InChIKey=IIOLGJUNCPGRSV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50280101   

TargetFibroblast growth factor receptor 3(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50280101(CHEMBL4061296)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of recombinant human His-tagged FGFR3 cytoplasmic domain (399 to 806 residues) expressed in baculovirus expression system using Tyr 04 as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2020
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50280101(CHEMBL4061296)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of recombinant human His-tagged FGFR1 cytoplasmic domain (308 to 731 residues) expressed in baculovirus expression system using Tyr 04 as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2020
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50280101(CHEMBL4061296)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant human His-tagged FGFR2 cytoplasmic domain (403 to 822 residues) expressed in baculovirus expression system using Tyr 04 as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2020
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50280101(CHEMBL4061296)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild type FGFR2 (unknown origin) (461 to 763 residues) transfected in Escherichia coli BL21(DE3) cells using Tyr04 peptide as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50280101(CHEMBL4061296)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of FGFR1 (unknown origin) (458 to 765 residues) transfected in Escherichia coli BL21(DE3) cells using Tyr04 peptide as substrate incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50280101(CHEMBL4061296)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of wild type FGFR3 (unknown origin) using Tyr04 peptide as substrate incubated for 1 hr by FRET based Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed