BDBM50278499 4-(7-(2,6-difluorophenylamino)thiazolo[4,5-d]pyrimidin-2-ylamino)benzenesulfonamide::CHEMBL513716

SMILES NS(=O)(=O)c1ccc(Nc2nc3ncnc(Nc4c(F)cccc4F)c3s2)cc1

InChI Key InChIKey=HGZQTJZFKROIJB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50278499   

TargetEpidermal growth factor receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50278499(4-(7-(2,6-difluorophenylamino)thiazolo[4,5-d]pyrim...)
Affinity DataIC50: 187nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50278499(4-(7-(2,6-difluorophenylamino)thiazolo[4,5-d]pyrim...)
Affinity DataIC50: 1.98E+4nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed