BDBM50278459 CHEMBL4176756

SMILES Cl.[H][C@]12Cc3ccccc3[C@@]1([H])[C@@]2([H])N[C@@H]1CC[C@H](N)CC1

InChI Key InChIKey=XLRHPTGCSRKMLO-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50278459   

TargetAmine oxidase [flavin-containing] A(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50278459(CHEMBL4176756)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected insect cells by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50278459(CHEMBL4176756)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of human recombinant N-terminal His/GST-tagged LSD1 (172 to 852 residues) expressed in baculovirus infected insect cells using biotin-labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50278459(CHEMBL4176756)
Affinity DataEC50: >20nMAssay Description:Inhibition of LSD1 in human MV-4-11 cells assessed as increase in CD86 mRNA expression after 3 days by SYBR Green dye-bsed RT-qPCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50278459(CHEMBL4176756)
Affinity DataEC50:  4.5nMAssay Description:Inhibition of LSD1 in human MV-4-11 cells assessed as increase in CD86 mRNA expression after 10 days by SYBR Green dye-bsed RT-qPCR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50278459(CHEMBL4176756)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected insect cells by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific histone demethylase 2(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50278459(CHEMBL4176756)
Affinity DataIC50: 4.51E+3nMAssay Description:Inhibition of human full length LSD2 using biotin-labeled H3K4me2 (1 to 24 residues) as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed