BDBM50277609 CHEMBL507312::[5-(6-Amino-9-isobutyl-2-methylsulfanyl-9H-purin-8-yl)-furan-2-yl]-phosphonic Acid

SMILES CSc1nc(N)c2nc(-c3ccc(o3)P(O)(O)=O)n(CC(C)C)c2n1

InChI Key InChIKey=WWOOHDHSIRZASU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50277609   

TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50277609([5-(6-Amino-9-isobutyl-2-methylsulfanyl-9H-purin-8...)
Affinity DataIC50: 700nMAssay Description:Inhibition of human liver FBPase expressed in Escherichia coli by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Rat)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50277609([5-(6-Amino-9-isobutyl-2-methylsulfanyl-9H-purin-8...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of rat liver FBPaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50277609([5-(6-Amino-9-isobutyl-2-methylsulfanyl-9H-purin-8...)
Affinity DataIC50: 7.00E+5nMAssay Description:Inhibition of human liver FBPase expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed